Reflections

Reflections

Making data and data-science more human:
Design’s collaboration with data scientists
calibrate the model features and endpoints user find most helpful

Aligning on I/O for handover purposes:
Aligning on what is input needed for the model to run and what are the possible outputs, smoothens the handover for front and back-end development

Co-creation builds adoption
Regular co-creation with power users and others along the design-prototype-build journey builds long-term adoption

View into the process

Reflections

Making data and data-science more human:
Design’s collaboration with data scientists
calibrate the model features and endpoints user find most helpful

Aligning on I/O for handover purposes:
Aligning on what is input needed for the model to run and what are the possible outputs, smoothens the handover for front and back-end development

Co-creation builds adoption
Regular co-creation with power users and others along the design-prototype-build journey builds long-term adoption

Context & Impact

Context & Impact

​Top PharmaCo was undergoing a global digital transformation of their R&D capabilities. Adapting their large molecule design capabilities to latest technologies is essential to meet patient needs and remain competitive.

60% of their R&D costs are driven by clinical failures. Out of 2.6 Bn USD development costs (accounted for failed assets), 1.5 Bn attributed to failed trials.

  • Insight synthesis of key personas across the mRNA-LNP design workflow including key responsibilities, pains and delights.

    Qualitative expert personas

    As is understanding

    Building application and adoption

  • Documenting the end to end workflow for chemists and biologist LNP researchers to identify the areas for ‘in-silico’ unlocks.

    Present-state workflow from desktop to lab

    As is understanding

  • Quantification of pain-points and gain-creators

    Documenting metrics around insights gathered to help prioritise ‘in-silico’ features.

    As is understanding

  • Considering the tech architecture together with the user’s workflow to identify key data flows and enabling user interfaces needed to make models usable.

    UX/UI Architecture design matching tech architecture

    Algorithmic supported workflow

  • Considering in-vivo and in-vitro workflows that can be complemented via in-silico workflows. Anchoring the future-state journey for both MVP and V1 launch of the product.

    Simplified ‘To-be’ workflow considering MVP and V1 releases

    Algorithmic supported workflow

  • Digital whiteboarding the user-stories and syndicating with leadership + translating them to UX/UI explorations

    Documenting key features as user-stories and high-fidelity wireframes

    Algorithmic supported workflow

  • Digital whiteboarding the user-stories and syndicating with leadership + translating them to UX/UI explorations

    Documenting key features as user-stories and high-fidelity wireframes

    Algorithmic supported workflow

  • Documenting validated user-stories and product features to helping plan sprints considering technical feasibility, business impact and user requirements.

    Maintaining product backlog for iterative deployment

    Building application and adoption

  • Conveying senior stakeholders bi-weekly for design and adoption sessions where built product is demo’ed and workflow implications are discussed.

    Conducting regular change management & adoption sessions

    Building application and adoption

  • Mapping future-state journeys across mRNA-LNP and other downstream teams to help cement hybrid workflows enabled by advanced analytical workflows.

    Envisioning cross-team collaboration enabled by in-silico workflows

    Building application and adoption

  • Insight synthesis of key personas across the mRNA-LNP design workflow including key responsibilities, pains and delights.

    Qualitative expert personas

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Documenting the end to end workflow for chemists and biologist LNP researchers to identify the areas for ‘in-silico’ unlocks.

    Present-state workflow from desktop to lab

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Documenting metrics around insights gathered to help prioritise ‘in-silico’ features.

    Quantification of pain-points and gain-creators

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Considering the tech architecture together with the user’s workflow to identify key data flows and enabling user interfaces needed to make models usable.

    UX/UI Architecture design matching tech architecture

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Considering in-vivo and in-vitro workflows that can be complemented via in-silico workflows. Anchoring the future-state journey for both MVP and V1 launch of the product.

    Simplified ‘To-be’ workflow considering MVP and V1 releases

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Digital whiteboarding the user-stories and syndicating with leadership + translating them to UX/UI explorations

    Documenting key features as user-stories and high-fidelity wireframes

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Documenting validated user-stories and product features to helping plan sprints considering technical feasibility, business impact and user requirements.

    Maintaining product backlog for iterative deployment

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Conveying senior stakeholders bi-weekly for design and adoption sessions where built product is demo’ed and workflow implications are discussed.

    Conducting regular change management & adoption sessions

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Mapping future-state journeys across mRNA-LNP and other downstream teams to help cement hybrid workflows enabled by advanced analytical workflows.

    Envisioning cross-team collaboration enabled by in-silico workflows

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Insight synthesis of key personas across the mRNA-LNP design workflow including key responsibilities, pains and delights.

    Qualitative expert personas

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Documenting the end to end workflow for chemists and biologist LNP researchers to identify the areas for ‘in-silico’ unlocks.

    Present-state workflow from desktop to lab

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Documenting metrics around insights gathered to help prioritise ‘in-silico’ features.

    Quantification of pain-points and gain-creators

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Considering the tech architecture together with the user’s workflow to identify key data flows and enabling user interfaces needed to make models usable.

    UX/UI Architecture design matching tech architecture

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Considering in-vivo and in-vitro workflows that can be complemented via in-silico workflows. Anchoring the future-state journey for both MVP and V1 launch of the product.

    Simplified ‘To-be’ workflow considering MVP and V1 releases

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Digital whiteboarding the user-stories and syndicating with leadership and translating them to UX/UI explorations

    Documenting key features as user-stories and high-fidelity wireframes

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Documenting validated user-stories and product features to helping plan sprints considering technical feasibility, business impact and user requirements.

    Maintaining product backlog for iterative deployment

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Conveying senior stakeholders bi-weekly for design and adoption sessions where built product is demo’ed and workflow implications are discussed.

    Conducting regular change management & adoption sessions

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

  • Mapping future-state journeys across mRNA-LNP and other downstream teams to help cement hybrid workflows enabled by advanced analytical workflows.

    Envisioning cross-team collaboration enabled by in-silico workflows

    As is understanding

    Algorithmic supported workflow

    Building application and adoption

Impact

  • ​Candidate drug in phase 1 trial expected to start 12-18 months after program start

    ​2x

  • Endpoint improvement over scientific baseline

    ​2-3x

  • ​Acceleration in the
    design of molecules

    ​>4x

  • In silico leads and vectors currently being tested in lab

    ​>1K

  • Research and data scientists using products daily

    ​50+

  • Of engagement with SMEs on
    UX and design topics

    520+ minutes

We integrated algorithms into a single digital product experience for analysis, tracking, and reporting of large molecules in-silico analysis.

Making Data Science Models Usable

Making Data Science Models Usable

We integrated algorithms into a single digital product experience for analysis, tracking, and reporting of large molecules in-silico analysis.

We integrated algorithms into a single digital product experience for analysis, tracking, and reporting of large molecules in-silico analysis.

We integrated algorithms into a single digital product experience for analysis, tracking, and reporting of large molecules in-silico analysis.

Life-Sciences

R&D Large Molecules

Life-Sciences

R&D Large Molecules

Life-Sciences

R&D Large Molecules

Life-Sciences

R&D Large Molecules

Life-Sciences

R&D Large Molecules

Life-Sciences

R&D Large Molecules